The article studies prospective for transformation of the current global deterrence system in 21 century, paying special attention to the structures of treaties past 2021.After the mainstay arms control treaty (New START) expiration development of the new system of treaties and agreements seems inevitable, quite possibly, on multilateral basis.The
Excessive risk-taking of financial agents drew a lot of attention in the aftermath of the financial crisis.Low interest rates and subdued market volatility during the Great Moderation are sometimes blamed for stimulating risk-taking and leading to the recent financial crisis.In recent years, with many central banks around the world conducting the p
A range of tissues have the capacity to adapt to mechanical challenges, an attribute presumed to be regulated through deformation of the cell and/or surrounding matrix.In contrast, it is shown here that extremely small oscillatory accelerations, applied as unconstrained motion and inducing negligible deformation, serve as an anabolic stimulus to os
Filoviruses infect a wide range of cell types with the exception of lymphocytes.The intracellular proteins cathepsin B and L, two-pore channel 1 and 2, and bona fide receptor Niemann–Pick Disease C1 (NPC1) are essential for the endosomal phase of cell entry.However, earlier steps of filoviral infection remain poorly characterized.Numerous pla
Recent advances in recombinant adeno-associated virus (rAAV) gene therapy for choroideremia show gene replacement to be a promising approach.It is, however, well known that contact of vector solution with plastic materials in the surgical device may result in non-specific adsorption with resulting loss of physical titer and/or level of protein expr